alkalosis and acidosis--is there and easy way to see how they work?
Q. I need to have a grasp of the normal values of metabolic/respiratory acidosis and alkalosis and how they all work. How do you discern is someone has alk/acidosis metabolically or via respiration and how do you tell if it is compensated? Can anyone tell me what patients with any of these problems would look like when you see them? Thanks VERY much in advance!
Asked by platform supporter - Thu Dec 25 13:36:49 2008 - - 1 Answers - 0 Comments

A. Hope you're sitting down. This is going to take a while. Carbon Dioxide and Bicarbonate form the basis of the PH in the blood. When co2 is released by the cells as waste it combines with h2o to form carbonic acid, H2CO3. This is a weak acid. To buffer this there is bicarbonate, HCO3. The H2CO3 loses a hydrogen ion in the lungs becoming H2O and CO2. The CO2 is released into the alveoli and exhaled. That hydrogen ion that was lost is picked up by the bicarbonate to form H2CO3 which again goes to the lungs etc. If there are too many hydrogen ions around the blood becomes acidotic and the body tries to compensate for this by making more bicarbonate to combine with the hydrogen ion. I assume you are a student in a Respiratory Therapy program… [cont.]
Answered by Dave - Thu Dec 25 14:47:56 2008

Why hypochloremic acidosis and bicarbonate administration? Why do we do this? ?
Q. Why hypochloremic acidosis and bicarbonate administration? Why do we do this?
Asked by derik103 - Mon Dec 1 23:23:42 2008 - - 1 Answers - 0 Comments
What is the difference between hyperlactatemia and lactic acidosis?
Q. What is the difference between hyperlactatemia and lactic acidosis?
Asked by tyd - Wed Sep 30 18:43:16 2009 - - 2 Answers - 0 Comments

A. They are the same thing.
Answered by Mojo - Wed Sep 30 20:54:18 2009

How might excessively high body temperature or acidosis interfere with enzyme activity?
Q. How might excessively high body temperature or acidosis interfere with enzyme activity?
Asked by tlc - Mon Oct 1 14:26:03 2007 - - 2 Answers - 0 Comments

A. ahh, easy one. Enzymes need very specific parameters to work in, if a body is too hot, too acidic, too basic, too cold. etc.. enzymatic reactions slow down and dont work correctly. SO, short answer.. if your body is too hot, certain enzymes will have a harder time working and same thing with a very acidic bloodstream.. enzymes not meant to work under a lower pH will suffer and your body processes that they run will also. Enzymes MUSt be under favorable conditions to work corrrectly
Answered by Peter Griffin - Mon Oct 1 14:30:47 2007

What is the significance of a normal high bicarbonate in respiratory acidosis?
Q. normal high means it is still within normal range, but on the high side
Asked by KANASAI - Tue Jun 2 03:39:18 2009 - - 2 Answers - 0 Comments

A. This means that the body is compensating for the acidosis. Respiratory acidosis is caused when carbon dioxide is not removed from the blood due to hypoventilation, (slow breathing) or obstructions in the exchange of gases. Such conditions are caused by emphysema, asthma, bronchitis, pneumonia and pulmonary edema. Carbon dioxide increases in the blood since it cannot effectively diffuse out of the lungs. The body has its own methods to correct abnormalities in pH. These are referred to as "compensation" methods. In a case of respiratory acidosis, the kidneys attempt to compensate for the low pH. The compensation is to increase excretion of H+ ion and therefore increase the retention or reabsorption of HCO3- (bicarbonate) into the blood.… [cont.]
Answered by HaLeZ - Tue Jun 2 04:02:31 2009

How can I distinguish between repiratory acidosis and metabolic acidosis?
Q. How can I distinguish between repiratory acidosis and metabolic acidosis?
Asked by Daisy - Tue Apr 15 12:33:05 2008 - - 3 Answers - 0 Comments

A. This is a simplified technique to determine the primary acid/base disorder. 1) Look at the pH. If it is >7.4, then the primary disorder is an alkalosis. If <7.4, it is acidosis. However, remember, a normal pH is 7.36-44. 2) Look at the pCO2. A normal pCO2 is ~40 mm Hg. If you have an acidosis and the pCO2 is high, then you have a primary respiratory acidosis (due to CO2 retention). If the pCO2 is low, then you have a metabolic acidosis. This is a very simplified guide to interpreting respiratory vs. metabolic acidosis.
Answered by Dr. C - Wed Apr 16 20:32:48 2008

Can some one explain to me High Anion Gap Metabolic Acidosis?
Q. OR please share a link where it is explained in a simple way. Thank you in advance.
Asked by blitzen - Thu Feb 5 09:25:40 2009 - - 1 Answers - 0 Comments

A. Metabolic acidosis is acid accumulation from increased acid production or acid ingestion, Causes are classified by their effect on the anion gap . The Anion Gap is an approximate measurement of ions, that is molecules with a charge, either negative or positive.The most common causes of a high anion gap metabolic acidosis are Ketoacidosis,Lactic acidosis, Renal failure, Toxic ingestions. Check out the link for more information on the above causes.
Answered by olhababy91 - Thu Feb 5 09:39:15 2009

ER did blood work but not looking for anything specific would they have seen if I had Lactic Acidosis?
Q. Accidentally took took double the Metformin XR for the last week and feel faint, dizzy, light headed and have slight leg cramping. I have also been on a plane for 6 hours on Tuesday. I went to the ER for dizziness and they couldn't find anything. Now I am worried about LA. I am so afraid, please help.
Asked by fu taitai! - Sun Dec 27 04:50:02 2009 - - 3 Answers - 0 Comments

A. I have only seen a few true cases of lactic acidosis from Metformin use. There are a couple things that can increase your risk for LA. If you are aware of your lab results, then one of the lab values you should look at is your serum creatinine (Scr) - if it is greater than 1.4 then you should not be taking Metformin any longer. Also, it is possible to directly measure the amount of lactate in the blood. I'm assuming that they would not have discharged you if it had been abnormal. Be aware that the recommend maximum dose for Metformin XR is 2000 mg per day.
Answered by MC, PharmD - Sun Dec 27 05:11:38 2009

What are the symptoms and treatment of mild or moderate respiratory acidosis?
Q. please help me
Asked by communication - Sat May 9 13:15:37 2009 - - 2 Answers - 0 Comments

A. The first symptoms of respiratory acidosis may be headache and drowsiness. Drowsiness may progress to stupor and coma. Stupor and coma can develop within moments if breathing stops or is severely impaired, or over hours if breathing is less dramatically impaired. The treatment of respiratory acidosis aims at improving the function of the lungs. Drugs that open the airways (bronchodilators, such as albuterol) may help people who have lung diseases such as asthma and emphysema. People who have severely impaired breathing or lung function, for whatever reason, may need mechanical ventilation to aid breathing. If the patient has a depressed respiratory system from overdose, narcotic administration, or neural origins, medication can be given… [cont.]
Answered by cryptoxmit - Sat May 9 15:47:00 2009

How does the renal system compensate for respiratory acidosis?
Q. How does the renal system compensate for respiratory acidosis?
Asked by cld4ever_always - Thu Mar 8 12:01:32 2007 - - 4 Answers - 0 Comments

A. Respiratory acidosis is a metabolic state often seen in COPD'ers. Patients with COPD are unable to properly secrete CO2 from their blood, and in exchange, they become acidotic due to the build up of hydrogen ions. Patients with renal failure are also prone to acidosis due to the damage in their kidneys. The kidneys are the body's main source of bicarb (HCO3) which helps to compensate (counteract) the effects of CO2. When a decrease in pH is detected, the kidneys begin to retain bicarb to compensate for the excess hydrogen ions in the blood. Unfortunately, compensation is a slow process and can often take several days. The pH level of the blood is maintained between 7.35 and 7.45. Levels below 7.35 are considered acidotic. CO2 (t [cont.]
Answered by CWinLV - Thu Mar 8 17:45:03 2007

how can metabolic acidosis or alkalosis arise?
Q. how can metabolic acidosis or alkalosis arise and how do these conditions shift the bicarbonate equilibrium. disscuss the body's compensatory mechanisms and treatment options to maintain homeostasis?
Asked by iSpar - Mon Sep 7 19:02:00 2009 - - 2 Answers - 1 Comments

A. are you in AP Bio? I had this exact question for hw this weekend
Answered by Inka - Tue Sep 8 00:42:21 2009

Is the student likely to be experiencing acidosis or alkalosis
Q. A student hyperventilates and is disoriented just before an exam. Is the student likely to be experiencing acidosis or alkalosis? How will the body compensate in an effort to maintain homeostasis?
Asked by tamtam - Thu Aug 7 14:25:52 2008 - - 2 Answers - 0 Comments

A. alkalosis. hyperventilation will remove excess CO2 from the body. When the CO2 is removed it shifts the bicarbonate buffer system equation to the right resulting in more C02/H20 and less HCO3- / H+ which raises the pH (alkalosis). The body could respond simply by hypoventilation which will reverse the process (there are a number of other ways the body can respond though).
Answered by GrizzlyMint - Thu Aug 7 14:38:57 2008

define ph and note the normal ph of blood? why is severe acidosis problematic?
Q. mrs. robers in a diabetic coma, has just been admitted to noble hospital. her blood ph indicates that she is in severe acidosis, and measures are quickly instituted to bring her blood ph back within normal limits
Asked by richal p - Wed Nov 19 21:25:47 2008 - - 1 Answers - 0 Comments

A. pH is the amount of free H+ present. Acidosis means that your blood is acidic. The normal pH of blood is 7.3 - 7.4.
Answered by derek k - Wed Nov 19 22:21:39 2008

The kidneys are removing excessive amounts of hydrogen ions is this acidosis or alkalosis?
Q. The kidneys are removing excessive amounts of hydrogen ions is this acidosis or alkalosis?
Asked by anitamono462 - Wed Jan 30 18:12:49 2008 - - 1 Answers - 0 Comments

A. This is not my area of study. However, removal of excess H+ would cause an alkaline condition so I would go for alkalosis.
Answered by Michael E - Wed Jan 30 18:24:15 2008

Does kidney failure necessarily mean the body is in metabolic acidosis?
Q. Does kidney failure necessarily mean the body is in metabolic acidosis?
Asked by anonymous - Tue Aug 12 06:13:46 2008 - - 3 Answers - 0 Comments

A. Yes. Kidney failure Lesions in Renal Tubular Epithelial Cells Excrete NH3 H+ Producing HCO3- Metabolic acidosis
Answered by Tony - Tue Aug 12 06:46:05 2008

Can inhaling carbon dioxide lead to respiratory acidosis?
Q. Can inhaling carbon dioxide lead to respiratory acidosis?
Asked by Tim - Thu Nov 19 21:58:58 2009 - - 1 Answers - 0 Comments
Why is NaCl given for respiratory acidosis or any other acid-base imbalances?
Q. Why is NaCl given for respiratory acidosis or any other acid-base imbalances?
Asked by Shenderella - Tue Feb 23 19:47:35 2010 - - 1 Answers - 0 Comments

A. It's usually only given when cardiac function is not impaired because of it AND when kidney function is adequate. Essentially, it allows the kidneys to take care of the problem by excreting either HCl or NH4Cl. Thus, the Cl is more important than the Na. Also, NaCl is often given whenever the patient needs fluids. By giving the Cl needed to help get rid of excess acids AND by giving fluids, it both helps any dehydration and give the kidneys plenty of fluids to filter out the excess acids.
Answered by biophilia - Tue Feb 23 19:54:12 2010

When a patient has metabolic acidosis from prolong diarrhea, why is there bicarbonate in his gut?
Q. When a patient has metabolic acidosis from prolong diarrhea, why is there bicarbonate in his gut?
Asked by shellnick8 - Thu Apr 3 19:06:26 2008 - - 3 Answers - 0 Comments

A. As Dr. L has pointed out the body produces Bicarb to help balance the acid not only in the stomach and the intestines but in the blood. Remember that because of cellular respiration you have O2 and CO2 circulating. However, prolonged diarrhea depletes the body of one of it's normal acid sources and due to the chronic nature the imbalance shifts to the basic or bicarb side of the pH scale as there are always buffers in the intestinal system. In order to treat this patient you need to not only treat the symptoms but the root cause (the diarrhea).
Answered by wezy53154 - Thu Apr 3 21:49:32 2008

Should I worry about Lactic acidosis if my leg got oddly stiff while I was sleeping today?
Q. I got really tired after I ate today, so I went to take a nap. My leg didn't get really numb or anything...it just cramped a little, so I moved to a different position...but like I said, when I woke up, I couldn't walk because my leg was so stiff... I take Metformin for PCOS
Asked by Amy A - Tue Aug 5 00:04:49 2008 - - 2 Answers - 0 Comments

A. Metformin typically causes lactic acidosis only when you've overdosed on it or your kidneys have shut down, if you're on the right dose and you're peeing ok and feeling otherwise well, i doubt it is lactic acidosis If you are really concerned a doc can do a quick blood test to rule it out (venous blood gas)
Answered by inzanium - Tue Aug 5 02:35:01 2008

How does Metabolic acidosis cause Kussmaul breathing?
Q. How does Metabolic acidosis cause Kussmaul breathing?
Asked by Paul - Wed Aug 19 19:04:40 2009 - - 1 Answers - 0 Comments

A. body response to blow off excess CO2
Answered by Chevi83 - Thu Aug 20 01:03:42 2009

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